New selective PAD4 inhibitors binding a calcium-deficient sort of the PAD4 enzyme have validated the important enzymatic position of human and mouse PAD4 in equally histone citrullination and neutrophil extracellular trap development for, to our know-how, the first time. The therapeutic possible of PAD4 inhibitors can now be explored. Compute https://alicea211kwg3.bloggactivo.com/profile