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Hepatic impairment: Minimize dosage in liver condition; lower the dosage of extended-launch sort to one-3rd or a single-half of the standard starting dosage; titrate to reaction May cause constipation, which may be problematic in clients with unstable angina and clients post-myocardial infarction; decrease the probable for constipation by administering stool https://wockusa.com/product/quagen-promethazine-hcl-and-codeine-phosphate-oral-solution/

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