Exogenously administered estrogens are metabolized in precisely the same fashion as endogenous estrogens. Metabolic transformation occurs mainly within the liver and intestine.15 Estradiol is metabolized to estrone, and the two are converted to estriol, that is later excreted in the urine. Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and https://ax-1583623109.thekatyblog.com/27491378/telaprevir-secrets